Fully Automated Next-Generation Capillary Electrophoresis

 

Introducing the V8 Nexus! A touch screen interface, user-defined, auto capillary conditioning, faster turnaround, integration of CE and zone data with the advanced reporting and tracking of the Myeloma Module and improved separation of protein and are just a few of the big advances of this system.

 

The V8 Nexus features eight capillaries and six on-board reagent positions that enable full multi-assay functionality and high throughput. A superior sample handling system allows continuous loading of samples with autodilutions and auto-preparation of SPIFE sample trays for additional testing by gel electrophoresis.

 

PLATINUM and QuickScan Software

Platinum 4V system software provides a comprehensive set of analytical tools and user-defined options for ease of operations. The V8 can also use QuickScan Touch densitometer software for editing, reviewing and reporting. Previous patient data from the QuickScan, such as IFE results, can be included on the capillary electrophoresis reports.

• Drive/control V8 functionality
• Advanced editing tools
• Statistical calculation and display
• Bi-directional communication with host network
• Multiple search parameters with overlay capacity
• Full audit trail accountability
• QC and validation using LeveyJennings

 

HIGHLIGHTED NEXUS FEATURES

 

Multi-Assay

Simultaneous separation of multiple assays using all eight capillaries and reagent positions

 

Auto Pilot

Select assays, load samples and close the lid – it’s as simple as that – all reagents and buffers are held on-board

 

Random Access

Continuous loading of up to 112 primary sample tubes for high throughput with the flexibility to insert urgent samples

 

QuickScan Software

Makes the management, analysis and interpretation of results simple, accurate and efficient, including bi-directional network communication. Same editing and reporting platform for both zone and CE for increased efficiency

 

Smart Sampling

Intelligent identification and recall of abnormal samples for confirmatory testing; integrated sample handling for gel electrophoresis preparation

 

Easy Audit

Total audit trail accountability including patient identification, reagent lot numbers and expiration dates, and security protection

 

Future Proof

Built-in flexibility for product evolution and a high-tech modular platform to provide supplementary chemistry space for buffers and reagents

 

Myeloma Module

Unifies current and historic patient data into a single portal for interpreting, tracking and reviewing; can be combined with SPIFE zone results

Identification	Positive patient identification. Sample rack bar coded identification. Bar code buffer and reagent containers.
Bar code	Embedded bar code reader. Symbologies: Code 39, Codabar, Code 128, Interleave 2 of 5, Code 93, UPC/EAN.
Loading	Up to 14 sample racks of 8 primary tubes; total 112 standard operation.
Gel sample trays	Compatible with SPIFE sample trays.
Sampling	Generic sample cups. Sampling is direct from uncapped primary tubes:                 - Diameter: max. 16 mm.                 - Height: max. 100 mm.                 - Dead volume: 30 µl.
Pre-analytical	Dilutions, cell lysis, reagent addition and reagent incubation
Migration	Eight silica-fused capillaries.  Peltier controlled temperature capillary chamber.
Buffers	Six on-board buffer system containers; up to four open user-defined assay buffer positions. Dynamic buffer level monitoring
Reagents	Ten open positions for reagents and antisera: Anti-IgG, -IgA, -IgM, kappa and lambda. Sample diluents and preparatory solutions. Peltier controlled reagent positions. Dynamic reagent level monitoring
Maintenance	On-board maintenance solutions. Automated maintenance, startup and shutdown procedures. Automated purging between assay changes.
Detection	Wavelength detection: monochromator with 200-600nm range Detection: eight photodiodes
Sensitivity	Detection of Serum Proteins at 20.8 mg/dL. (23 mg/dL Fast CE)

Assays/throughput/tests per kit
Serum Protein 6-band Serum Protein 6-band Fast CE Immunodisplacment	48/hr 88/hr 14/hr	500 500 50

Data processing	Database management of up to 2 million patient scans. Export to QuickScan Touch for edit and reporting. Trace capture and editing. Statistical calculation and display. Database flagging of patient status. Bi-directional communication; import and export of patient data. Immunodisplacement image capture & linkage to scan traces. Multiple search parameters with overlay capacity
Q.C. and validation	Levey-Jennings and statistics reports
Dimensions	35.2" (width) × 26.8" (depth) × 26.8" (height).  895 mm (width) x 680 mm (depth) x 680 mm (height)
Weight	159 lbs. / 72 kg.
Connections	Output connections Ethernet connection from V8 to PC, LIS. RS232 serial connection to LIS. USB connection to peripheral utilities.
Power	Consumption of 489 W (VA)
Environmental operating conditions	Ambient temperature 15 to 30°C (59°F to 86°F). Non-condensing relative humidity between 35% and 88%. Maximum altitude of 6,562' (2000 meters).

Helena V8 Nexus Capillary Electrophoresis